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《DIC彌漫性血管內凝血-北京協和醫(yī)院血液科》專家PPT內容預覽
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《DIC彌漫性血管內凝血-北京協和醫(yī)院血液科》專家PPT內容簡介
    Disseminated Intravascular Coagulation
    DIC是一種發(fā)生于多種疾病或特殊病理狀態(tài)下，人體凝血系統被激活而引起中小血管內彌漫性微血栓形成及繼發(fā)性纖溶亢進的綜合征。
    由于DIC發(fā)展過程中出現不同程度的血小板和凝血因子水平消耗性減少，也稱之為“消耗性凝血病”或“消耗性血栓出血性疾病”。

    Clinical conditions associated with DIC 
    1. Sepsis/Severe infection --- -------- 44.6%
    2. Malignancy ------------------------- 20.7%
    Solid tumors 6.9%，AL 13.8%. Occurrence in APL 37~65%. 
    3. Obstetrical calamities ------------ 13.4%
    Amniotic fluid embolism, Abruptio placentae, Dead fetus
    4. Trauma / Surgery ----------------- 7.4% 
    5. Severe hepatic failure ------------ 7.4% 
    6. Vascular abnormalities
    Kasabach-Merritt syndrome，Large vascular aneurysms
    7. Organ destruction (e.g., severe pancreatitis)
    8. Severe toxic or immunologic reactions
    Snake bites，Recreational drugs，Transfusion reactions，Transplant rejection

    Mortality
    DIC----Death Is Coming.
    Mortality ranges from 31~86%, whether or not heparin was administrated.
    Correlated Factors:
    Underlying disorders
    The extent of orgon dysfuction
    The degree of hemostatic failure
    Increasing age

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